Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6483502 | Acta Biomaterialia | 2015 | 24 Pages |
Abstract
(a) Targeted magnetic nanoparticles bind to cell surface and are internalized into lysosomes. (b) AMF activation induces lysosomal permeability triggering cellular death. (c) Nanoparticle coating inhibits Fenton-like chemistry indicating a thermal or mechanical effect causes the lysosomal disruption.265
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Authors
Robert J. Wydra, Piotr G. Rychahou, B. Mark Evers, Kimberly W. Anderson, Thomas D. Dziubla, J. Zach Hilt,