Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6483790 | Acta Biomaterialia | 2015 | 13 Pages |
Abstract
The addition of matrix metalloproteinases (MMPs) can trigger the long-term stable release of mTGF-β3 from the recombinant fusion protein of LAP-MMP-mTGF-β3 in the combined scaffolds, thus stimulating the differentiation of ADSCs into cartilage, which was confirmed by histological analysis, indicating the great potential of this hybrid in rapid therapy of osteoarthritis.78
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Dong Zheng, Yang Dan, Shu-hua Yang, Guo-hui Liu, Zeng-wu Shao, Cao Yang, Bao-jun Xiao, Xiangmei Liu, Shuilin Wu, Tainjin Zhang, Paul K. Chu,