Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6484104 | Biochemical Engineering Journal | 2013 | 8 Pages |
Abstract
- An efficient UPLC/Q-TOF MS method was developed to profile taxoids in Taxus cells.
- A total of 21 taxoids was detected in Taxus cells.
- It is the first case study on the effect of shear stress on taxoids metabolism.
- The possible mechanism for shear stress limiting taxol production was proposed.
- This work has important biotechnological applications to increase paclitaxel yields.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Pei-pei Han, Ting-xiang Ye, Bin Qiao, Ying-jin Yuan,