Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6484556 | Biomaterials | 2018 | 32 Pages |
Abstract
Inspired by the ability of eukaryote to package millions of genes in the nucleus wrapping and condensing DNA around histones to form chromosomes, here we developed a karyon-like hybrid nanocarrier. By utilizing the fullerenol assembled with Dox, the polymeric nanoparticles achieved appreciable therapeutic efficiency with high encapsulation efficiency and reduced side effects.328
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Authors
Jinglong Tang, Ruirui Zhang, Mengyu Guo, Leihou Shao, Ying Liu, Yuliang Zhao, Suojiang Zhang, Yan Wu, Chunying Chen,