| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6484576 | Biomaterials | 2018 | 27 Pages |
Abstract
In this work, bacterial-like mesoporous silica-coated gold nanorods (bGNR@MSN) were successfully synthesized and used for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined cancer therapy. The results showed bGNR@MSN(DOX)-PEG mediated chemo-photothermal combined treatment exhibited significantly enhanced therapeutic efficacy in 4T1 tumor-bearing mice due to their excellent photothermal effects, high-efficiency DOX loading, NIR-triggered DOX release capacity and high tumor accumulation (â¼10 %ID/g).548
Keywords
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Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Cheng Xu, Feng Chen, Hector F. Valdovinos, Dawei Jiang, Shreya Goel, Bo Yu, Haiyan Sun, Todd E. Barnhart, James J. Moon, Weibo Cai,