| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6484603 | Biomaterials | 2018 | 12 Pages |
Abstract
A photo-tearable tape wrapped UCNP nanocapsule loaded with siRNA and photosensitizer is designed for NIR light modulated gene therapy. The high photocleavage efficiency by tape close wrapping via a synthesized photocleavable linker and ROS boosted endosomal escape of siRNA result in impressive improvement for gene therapy efficiency both in vitro and in vivo.295
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Authors
Yue Zhang, Kewei Ren, Xiaobo Zhang, Zhicong Chao, Yuqin Yang, Deju Ye, Zhihui Dai, Ying Liu, Huangxian Ju,