| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6484888 | Biomaterials | 2016 | 47 Pages |
Abstract
Herein we present a multifunctional DNA origami as biocompatible nanocarrier of ruthenium complexes (RuPOP) for advanced cancer therapeutics. The tetrahedral Bio-cage with cancer-targeted ability increases the loading efficacy of RuPOP and drastically promotes its tumoral accumulation. Bio-cage@Ru undergoing safe circulation in blood efficiently targets nucleus and strengthens enhanced antitumoral effects without causing systemic toxicities.268
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Yanyu Huang, Wei Huang, Leung Chan, Binwei Zhou, Tianfeng Chen,