Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6485226 | Biomaterials | 2016 | 9 Pages |
Abstract
A reciprocal relationship was found between activation of the contact system and the complement system induced by the polymers studied here. The ratios of FXII/C1INH or C4/C4BP, adsorbed from EDTA-plasma are useful surrogate markers for cytokine release and inflammatory response to materials intended for blood contact.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Shan Huang, Anna E. Engberg, Nina Jonsson, Kerstin Sandholm, Ian A. Nicholls, Tom Eirik Mollnes, Karin Fromell, Bo Nilsson, Kristina N. Ekdahl,