Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

Article ID	Journal	Published Year	Pages	File Type
6486540	Biotechnology Advances	2018	89 Pages	PDF

Keywords

ECM AMPK NF-κB PI3K PTM AHR LPS Jnk Nrf2 UGT GST EGCG PPI mTOR MAF ERK iNOS HFD LDLR Epigallocatechin-3-gallate PPAR eNOS IRS STZ UPR TGF Retinoid X receptor Dnmt GSK NQO1 RXR HMOX-1 FGF21 G6PDH βTrCP Jun-N-terminal kinase NEH TNF γGCS keap1 CDDO-Im CDDO-Me DNA methyltransferase MAPK NAD(P)H quinone dehydrogenase 1 ROS UDP-glucuronosyltransferase Cellular stress streptozotocin posttranslational modification insulin receptor substrate interleukine Bardoxolone methyl β-Cell function transforming growth factor Protein-protein interaction Insulin sensitivity db/db Diabetes mellitus Type 2 diabetes High fat diet SOD Age inducible nitric oxide synthase endothelial nitric oxide synthase Superoxide dismutase Ubiquitin proteasome system extracellular signal regulated kinase endoplasmic reticulum antioxidant response element Vascular complications fibroblast growth factor 21 tumor necrosis factor nuclear factor (erythroid-derived 2)-like 2 Natural products cul phosphoinositide-3-kinase lipopolysaccharide Extracellular matrix Methylglyoxal Advanced glycation end products Genome-wide association studies GWAS knockout Hyperglycemia mammalian target of rapamycin ARE heme oxygenase 1 Kelch-like ECH-associated protein 1 Protein kinase protein kinase RNA-like endoplasmic reticulum kinase PERK Single nucleotide polymorphism SNP Cullin 3 AMP-activated kinase mitogen-activated kinase glutathione-S-transferase glutathione reductase glucose-6-phosphate dehydrogenase glycogen synthase kinase Reactive oxygen species arylhydrocarbon receptor peroxisome proliferator-activated receptor low density lipoprotein receptor UPS

Related Topics

Physical Sciences and Engineering Chemical Engineering Bioengineering

Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

Authors

Manuel Matzinger, Katrin Fischhuber, Elke H. Heiss,