Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6486549 | Biotechnology Advances | 2018 | 39 Pages |
Abstract
In this review, we summarize and discuss recent research aiming to integrate enzyme immobilization and protein engineering and propose strategies to further converge protein engineering and enzyme immobilization efforts into a novel “immobilized biocatalyst engineering” research field. We believe that through the integration of both enzyme engineering and enzyme immobilization strategies, novel biocatalysts can be obtained, not only as the sum of independently improved intrinsic and operational properties of enzymes, but ultimately tailored specifically for increased performance as immobilized biocatalysts, potentially paving the way for a qualitative jump in the development of efficient, stable biocatalysts with greater real-world potential in challenging bioprocess applications.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Claudia Bernal, Karen RodrÃguez, Ronny MartÃnez,