| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487129 | Computational Biology and Chemistry | 2013 | 7 Pages |
Abstract
- Simulation of the first two reactions in the LPS pathway.
- Kinetic parameters were obtained from the literature whilst others were estimated from our simulations.
- The possibility of the unfavourable equilibrium constant in the first step of the LPS pathway was analyzed.
- The mechanism of LpxC regulation by FtsH activation was investigated using differential time trigger in our model.
- Under extreme increases in LpxC concentration, FtsH is incapable of regulating production of excess end-product.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Akintunde Emiola, Paolo Falcarin, Joanne Tocher, John George,