| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487447 | Current Opinion in Biotechnology | 2016 | 7 Pages |
Abstract
- Disseminated tumor cells can be found in the majority of prostate cancer patients, even without clinical evidence of metastatic disease.
- The identity and characteristics of circulating and disseminated tumor cells remain unclear.
- Autocrine and paracrine signals are likely needed to induce a proliferative switch in dormant prostate cancer DTCs.
- Therapies to 'treat' DTCs need to be developed.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Emma E van der Toom, James E Verdone, Kenneth J Pienta,