| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487451 | Current Opinion in Biotechnology | 2016 | 7 Pages |
Abstract
- Development of anti-fibrotic treatments is hampered by culture system limitations.
- Fibrosis involves ECM disarray, TGF-β1 signaling, and matrix stiffening.
- Tunable 3-D engineered structures can recapitulate the aforementioned features.
- Novel imaging and sensor tools can allow visualization of matrix dynamics in vitro.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Ana M Porras, Heather N Hutson, Anthony J Berger, Kristyn S Masters,