| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487603 | Current Opinion in Biotechnology | 2016 | 9 Pages |
Abstract
- Recombinant lytic enzymes have several advantages over bacteriophage treatments.
- Types and sources of binding and catalytic domains greatly impact lysin efficacy.
- Viral enzymes and bacterial autolysins offer diverse reservoirs for recombination.
- Lysins hold promise for being tailored to specific applications with careful design.
- Enzyme architecture, cell physiology, and environment are key design considerations.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Maxwell L Van Tassell, M Angela Daum, Jun-Seob Kim, Michael J Miller,