| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487685 | Current Opinion in Biotechnology | 2015 | 7 Pages |
Abstract
- Transcription factors are approved sensors to monitor intracellular concentrations.
- Sensors coupled to gfp expression convert concentrations into a graded signal.
- Combination of FACS and sensors enable selection of target-molecule-producing microorganisms.
- NAD(P)H-responsive sensors offer generalizable screens for NAD(P)H-dependent enzymes.
- Recombineering plus sensors unite diversity generation and producer selection.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Lothar Eggeling, Michael Bott, Jan Marienhagen,