Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6487692 | Current Opinion in Biotechnology | 2015 | 9 Pages |
Abstract
- The global epidemic of interrelated metabolic diseases is dramatically increasing.
- Closed-loop prosthetic gene circuits may be used for the treatment of metabolic disorders.
- Prosthetic networks could functionally integrate and interface with host cell metabolism.
- Prosthetic networks could self-sufficiently monitor disease states and automatically provide therapy.
- Prosthetic networks may compare favourably with classical pharmacotherapy.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Boon Chin Heng, Dominique Aubel, Martin Fussenegger,