| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487716 | Current Opinion in Biotechnology | 2015 | 7 Pages |
Abstract
- Oncogenic and microenvironmental stimuli rewire metabolism in cancer cells.
- Many chromatin-modifying enzymes rely on metabolites as cofactors or substrates.
- Histone acetylation is sensitive to acetyl-CoA levels, and linked to growth and proliferation.
- Histone methylation is sensitive to the methyl donor S-adenosylmethionine.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Alessandro Carrer, Kathryn E Wellen,