Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6487723 | Current Opinion in Biotechnology | 2015 | 7 Pages |
Abstract
- Transcriptional engineering provides tight control of gene expression in eukaryotes.
- Synthetic promoters provide iterative improvements in strength.
- Orthogonal transcription factors provide the greatest range of expression.
- Genetic context plays an important role in determining expression levels.
- Robustness of genetic parts will enable more reliable genetic circuits.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
John M Leavitt, Hal S Alper,