Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6487737 | Current Opinion in Biotechnology | 2015 | 13 Pages |
Abstract
- 13C tracer analysis can be used to probe intracellular metabolism in cells.
- Steady state labeling patterns can quantify nutrient contributions.
- Steady state labeling patterns can inform about pathway activities.
- Dynamic labeling patterns combined with metabolite levels can quantify some fluxes.
- Analysis of multiple metabolites and various tracers enhances information output.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Joerg M Buescher, Maciek R Antoniewicz, Laszlo G Boros, Shawn C Burgess, Henri Brunengraber, Clary B Clish, Ralph J DeBerardinis, Olivier Feron, Christian Frezza, Bart Ghesquiere, Eyal Gottlieb, Karsten Hiller, Russell G Jones, Jurre J Kamphorst,