Article ID Journal Published Year Pages File Type
6487809 Current Opinion in Biotechnology 2015 9 Pages PDF
Abstract

- Mass spectrometry is a versatile alternative to colorimetric enzyme activity assays.
- Technologies developed for MSI can be applied to high-throughput enzyme screening.
- Analyte immobilization allows for activity determination in complex sample matrices.
- Such methods along with selective derivatization reactions enable label-free assays.
- These advances could aid the spatial localization of enzymatic activity with MSI.
Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
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