Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6487809 | Current Opinion in Biotechnology | 2015 | 9 Pages |
Abstract
- Mass spectrometry is a versatile alternative to colorimetric enzyme activity assays.
- Technologies developed for MSI can be applied to high-throughput enzyme screening.
- Analyte immobilization allows for activity determination in complex sample matrices.
- Such methods along with selective derivatization reactions enable label-free assays.
- These advances could aid the spatial localization of enzymatic activity with MSI.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Tristan de Rond, Megan Danielewicz, Trent Northen,