| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487843 | Current Opinion in Biotechnology | 2014 | 8 Pages |
Abstract
- Modular polyketide synthases have the potential to produce many existing and novel compounds.
- Accessible compounds include several commodity chemicals with large markets.
- The potential of polyketide synthases greatly surpasses our current ability to engineer them.
- We suggest adopting a design-build-test-learn paradigm for engineering polyketide synthases.
- We suggest several strategies to improve the design-build-test-learn cycle.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Sean Poust, Andrew Hagen, Leonard Katz, Jay D Keasling,