Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6487890 | Current Opinion in Biotechnology | 2014 | 7 Pages |
Abstract
- Kinetic models are crucial to understand complex dynamic processes.
- Not all model parameters need to be known precisely due to overlapping regulatory layers.
- Including regulatory interactions are crucial.
- Ensemble modeling enables unbiased identification of key regulatory interactions.
- Paradigm shift from fitting parameters towards identifying key regulatory interactions.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Hannes Link, Dimitris Christodoulou, Uwe Sauer,