| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6487908 | Current Opinion in Biotechnology | 2014 | 9 Pages |
Abstract
- Recent in silico and experiment-guided genome mining strategies are highlighted.
- Homology-based and genome sequencing-independent approaches to target polyketides are described.
- Strategies for polyketide discovery guided by synthetic biology and metabolic/genetic engineering.
- Complementing the advances in genome mining, next generation analytical approaches are discussed.
- Pathogens, mutualists, anaerobes and uncultured bacteria are biosynthetically prolific.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Eric JN Helfrich, Silke Reiter, Jörn Piel,