Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6491478 | Journal of Biotechnology | 2014 | 8 Pages |
Abstract
- Porcine parvovirus (PPV) was aggregated with osmolytes and removed with microfiltration.
- 96% of PPV was removed in 3.0Â M glycine at a pH of 5.
- Flocculation is specific to virus particles, making it a potential method to purify the virus from host cell proteins.
- Microfiltration is often used to retain bacteria, and therefore this is a unique application for small virus removal.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Maria F. Gencoglu, Eric Pearson, Caryn. L. Heldt,