Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6491856 | Journal of Biotechnology | 2013 | 11 Pages |
Abstract
⺠We develop a mathematical model for adherent cell growth in numbers and size. ⺠The model is suited to simultaneously describe three independent cultivations. ⺠We evaluate cell growth phases in terms of cell number and cell volume increase. ⺠Precise estimation of parameters reveals time dependent demands for substrates. ⺠Cellular glucose uptake correlates with glucose 6-phosphate dynamics.
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Authors
M. Rehberg, J.B. Ritter, Y. Genzel, D. Flockerzi, U. Reichl,