| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6492004 | Journal of Biotechnology | 2012 | 9 Pages |
Abstract
⺠Chinese Hamster Ovary (CHO) cells adapted for growth in suspension are a valuable tool for the medium scale production of recombinant protein. ⺠Addition of l-cystine to the culture medium of CHO-S cells increases the formation of disulphide bonds in LAP-fusion proteins. ⺠Use of the SV40 large T antigen to increase plasmid copy number increases the production of recombinant protein in CHO cells.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Lisa M. Mullen, Gill Adams, Yuti Chernajovsky,