| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6492059 | Journal of Biotechnology | 2012 | 8 Pages |
Abstract
⺠The effect of ROS-mediating pO2 on HSPCs gene expression was studied by microarrays. ⺠Cells differentiation genes were down-regulated in hypoxia or reducing ROS group. ⺠Three genes related to dendritic cells maturation were confirmed by real-time PCR. ⺠Mature potential of DCs was suppressed by hypoxia-reducing ROS in further study. ⺠Hypoxia-reducing ROS regulated the genes driving HSPCs differentiation.
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Authors
Jinli Fan, Haibo Cai, Qunliang Li, Zheng Du, Wensong Tan,