Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6492077 | Journal of Biotechnology | 2012 | 6 Pages |
Abstract
⺠Over-expression of folate gene cluster increased folate concentration 8 times. ⺠Cell density and 2-KGA production increased by 18% and 14% in shake flasks. ⺠A 25% cell density and 35% 2-KGA productivity enhancement was observed in fermentor. ⺠This was the first successful study of metabolic engineering on K. vulgare.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Lei Cai, Mei-Qing Yuan, Zheng-Jun Li, Jin-Chun Chen, Guo-Qiang Chen,