| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6492094 | Journal of Biotechnology | 2012 | 14 Pages |
Abstract
⺠We propose a new system for expression of antigens fused with the OprI lipoprotein. ⺠It offers tight control of expression and metal affinity chromatography purification. ⺠The OprI expressed by the system is triacylated, mainly by palmitic acid residues. ⺠The cloned antigens can be obtained in three bacterial cell wall-derived formulations. ⺠Applications include studies on immunization and on modulation of acquired immunity.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Afonso P. Basto, João Piedade, Ruben Ramalho, Susana Alves, Helena Soares, Pierre Cornelis, Carlos Martins, Alexandre Leitão,