Article ID Journal Published Year Pages File Type
6492195 Journal of Biotechnology 2011 4 Pages PDF
Abstract
► Hyperosmolality in CHO cell cultures induces autophagy and apoptosis. ► Bcl-xL overexpression delays autophagy/apoptosis in hyperosmotic CHO cell cultures. ► Bcl-xL overexpression improves cell viability and EPO production at hyperosmolality.
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Physical Sciences and Engineering Chemical Engineering Bioengineering
Preview
Bcl-xL overexpression delays the onset of autophagy and apoptosis in hyperosmotic recombinant Chinese hamster ovary cell cultures
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