| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6493944 | Journal of Photochemistry and Photobiology B: Biology | 2013 | 8 Pages |
Abstract
⺠MS2 bacteriophages are used as nanoscale delivery vessels for photodynamic therapy agents. ⺠Cationic porphyrins are loaded inside the capsid via nucleotide-driven packaging. ⺠G-rich oligonucleotide aptamers are conjugated to capsid exterior to instill cell-selectivity. ⺠Porphyrin-loaded MS2 decorated with aptamers exhibit cell-specific PDT capability in vitro.
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Authors
Brian A. Cohen, Magnus Bergkvist,