Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6494380 | Metabolic Engineering | 2015 | 42 Pages |
Abstract
The most promising and yet challenging application of microalgae and cyanobacteria is the production of renewable energy: biodiesel from microalgae triacylglycerols and bioethanol from cyanobacteria carbohydrates. A thorough understanding of microalgal and cyanobacterial metabolism is necessary to master and optimize biofuel production yields. To this end, systems biology and metabolic modeling have proven to be very efficient tools if supported by an accurate knowledge of the metabolic network. However, unlike heterotrophic microorganisms that utilize the same substrate for energy and as carbon source, microalgae and cyanobacteria require light for energy and inorganic carbon (CO2 or bicarbonate) as carbon source. This double specificity, together with the complex mechanisms of light capture, makes the representation of metabolic network nonstandard. Here, we review the existing metabolic networks of photoautotrophic microalgae and cyanobacteria. We highlight how these networks have been useful for gaining insight on photoautotrophic metabolism.
Keywords
F6P3PGPEPGDSFVACEFG2pAEFTCAEFMFBAG6PFlux coupling analysisR5P3-phosphoglycerateTAGsFlux balance analysisTriacylglycerolsLinear electron flowCyclic electron flowElementary flux modesribose 5-phosphateMetabolic networkGAPFcafructose-6-phosphatephosphoenolpyruvateLefMetabolic modelingLipidsCitric acid cycleCarbohydratesGlucose 6-phosphateglyceraldehyde 3-phosphate
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Caroline Baroukh, Rafael Muñoz-Tamayo, Jean-Philippe Steyer, Olivier Bernard,