Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6531193 | Journal of Molecular Catalysis B: Enzymatic | 2014 | 8 Pages |
Abstract
- Genes encoding 'Type II FMOs' CFMO and PSFMO were selected for diversity in the NADPH binding loop.
- CFMO and PSFMO were shown to both accept either NADH or NADPH as cofactor in the reduction of FAD.
- The activities with both NADPH and NADH have been evaluated in the oxidation of sulfide substrates.
- Structures of CFMO and PSFMO were solved, revealing the nature of the NADPH phosphate binding loop.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Chantel N. Jensen, Sohail T. Ali, Michael J. Allen, Gideon Grogan,