| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6531208 | Journal of Molecular Catalysis B: Enzymatic | 2014 | 5 Pages |
Abstract
- Synthesis of Valganciclovir intermediate enzymatically has been reported.
- Selective hydrolysis of Cbz protected di-ester of Ganciclovir to produce monoester is carried out.
- Protex-6L, a commercially available and cheap enzyme is used.
- The valganiclovir intermediate prepared is a key intermediate of anti-viral drug, valganciclovir hydrochloride.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Madhuresh K. Sethi, Somashekar R. Bhandya, Rohit Shukla, Anish Kumar, Nagaraj Maddur, V.S.N. Jayalakshmi Mittapalli, Vijendra Singh Rawat, Raja Krishna Yerramalla,