| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6601371 | Electrochemistry Communications | 2014 | 15 Pages |
Abstract
A disposable electrochemical biosensor for the determination of l-DOPA in undiluted human serum is described. It is based on the use of a carbon nanotubes-modified screen printed electrode covered with an electropolymerized poly(thionine) film and an outer cross-linked layer containing tyrosinase. Further coverage of the sensor with a Nafion layer allows its use directly in human serum, obviating the need for sample pretreatment. The sensor exhibited a linear behavior in the 0.8-22 μM concentration range and offers promise for decentralized clinical testing of l-DOPA.
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Authors
Barbara Brunetti, Gabriela Valdés-RamÃrez, Irene Litvan, Joseph Wang,