Symptom dimensions and subgroups in childhood-onset schizophrenia

Article ID	Journal	Published Year	Pages	File Type
6820560	Schizophrenia Research	2018	7 Pages	PDF

Abstract

Our analysis found distinct symptom-based subgroups within the NIMH COS cohort using an established AOS symptom structure. These findings confirm the heterogeneity of COS and were generally consistent with AOS literature.

Keywords

ASQ K-SADS Tucker Lewis Index BPRS CNVs RMSEA TLI CFA PANSS PDD COS Cgas SAPs GFI CFI Early onset schizophrenia Symptom dimensions Oppositional Defiant Disorder pervasive developmental disorder Conduct disorder attention deficit hyperactivity disorder autism spectrum disorders childhood-onset schizophrenia SANS AOS ADHD Confirmatory Factor Analysis goodness of fit index Root mean square error of approximation Subgroups Comparative Fit Index Copy number variants EOs ODD Scale for the Assessment of Positive Symptoms Scale for the Assessment of Negative Symptoms Brief Psychiatric Rating Scale Positive and Negative Symptom Scale National Institute of Mental Health Symptomatology ASD NIMH

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Symptom dimensions and subgroups in childhood-onset schizophrenia

Authors

Kirsten E.S. Craddock, Xueping Zhou, Siyuan Liu, Peter Gochman, Dwight Dickinson, Judith L. Rapoport,