Article ID Journal Published Year Pages File Type
6822982 Schizophrenia Research 2016 8 Pages PDF
Abstract
White matter deficits were validated in the present study by a relatively large sample of medication naïve and first episode schizophrenia patients. They could be associated with negative symptoms and cognitive impairment, whereas improvement in white matter integrity of left superior longitudinal fasciculus correlated with improvement in psychosis and processing speed. Further examination of treatment-related changes in white matter integrity may provide clues to the mechanism of antipsychotic response and provide a biomarker for clinical studies.
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
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