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AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study

Article ID Journal Published Year Pages File Type
6823112 Schizophrenia Research 2016 6 Pages PDF
Abstract
These results do not support a role for the mGluR-2 PAM AZD8529 as an antipsychotic and indicate that positive modulation of mGluR type 2 receptors alone is not sufficient for antipsychotic effects in acutely ill schizophrenia patients.
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Life Sciences Neuroscience Behavioral Neuroscience
Preview
AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study
Authors
Robert E. Litman, Mark A. Smith, James J. Doherty, Alan Cross, Shane Raines, Lev Gertsik, Stephen R. Zukin,
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Journal
Schizophrenia Research
Journal: Schizophrenia Research
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