Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6823760 | Schizophrenia Research | 2015 | 8 Pages |
Abstract
Our findings are consistent with the possibility that antipsychotic medication exposure and time spent in relapse partially explain progressive brain reductions in schizophrenia. However, residual confounding could also account for the findings and caution must be applied before drawing causal inferences from associations demonstrated in observational studies of modest size. Less progressive brain volume loss in schizophrenia may indicate better preserved social and occupational functions.
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Behavioral Neuroscience
Authors
Joyce Y. Guo, Sanna Huhtaniska, Jouko Miettunen, Erika Jääskeläinen, Vesa Kiviniemi, Juha Nikkinen, Jani Moilanen, Marianne Haapea, Pirjo Mäki, Peter B. Jones, Juha Veijola, Matti Isohanni, Graham K. Murray,