| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6823923 | Schizophrenia Research | 2015 | 6 Pages |
Abstract
Our results suggest that FEP is accompanied by a cytokine profile indicative of monocytic and T regulatory cell (Treg) activation. Depression in FEP is accompanied by monocytic and Th-2 activation, whereas FEP without depression is characterized by Treg activation only. In conclusion, depression emerged as a key component explaining the cytokines imbalance in FEP that is responsible for a large part of the immune-inflammatory abnormalities described.
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Authors
Cristiano Noto, Vanessa Kiyomi Ota, Marcos Leite Santoro, Bruno B. Ortiz, Lucas B. Rizzo, Cinthia Hiroko Higuchi, Quirino Cordeiro, Sintia Iole Belangero, Rodrigo Affonseca Bressan, Ary Gadelha, Michael Maes, Elisa Brietzke,