Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6823992 | Schizophrenia Research | 2015 | 12 Pages |
Abstract
Existing literature does not elucidate neuroimaging correlates specific to TRS or URS, which, if present, might also shed light on clozapine's efficacy in TRS. This said, leads from other lines of investigation, including the glutamatergic system can prove useful in guiding future neuroimaging studies focused on, in particular, the frontocortical-basal ganglia-thalamic circuits. Critical to the success of this work will be precise subtyping of study subjects based on treatment response/nonresponse and the use of multimodal neuroimaging.
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Authors
Shinichiro Nakajima, Hiroyoshi Takeuchi, Eric Plitman, Gagan Fervaha, Philip Gerretsen, Fernando Caravaggio, Jun Ku Chung, Yusuke Iwata, Gary Remington, Ariel Graff-Guerrero,