Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6824714 | Schizophrenia Research | 2014 | 9 Pages |
Abstract
In adolescents with schizophrenia and bipolar disorder with psychotic symptoms there is cortical thinning, decreased GI and increased sulcal width of the frontal cortex present at the time of the first psychotic episode. Decreased frontal GI is associated with the widening of the frontal sulci which may reduce sulcal surface area. These results suggest that abnormal growth (or more pronounced shrinkage during adolescence) of the frontal cortex represents a shared endophenotype for psychosis.
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Behavioral Neuroscience
Authors
Joost Janssen, Yasser Alemán-Gómez, Hugo Schnack, Evan Balaban, Laura Pina-Camacho, Fidel Alfaro-Almagro, Josefina Castro-Fornieles, Soraya Otero, Inmaculada Baeza, Dolores Moreno, Nuria Bargalló, Mara Parellada, Celso Arango, Manuel Desco,