| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6825526 | Schizophrenia Research | 2014 | 8 Pages |
Abstract
A correlation between reduction in 5-HTT expression and DNA hypermethylation of the 5-HTT promoter in drug naïve SCZ patients suggests that an epigenetically defined hypo-activity of 5-HTT may be linked to SCZ pathogenesis. Furthermore, this epigenetic mark in DNA extracted from saliva can be considered as one of the key determinants in a panel of diagnostic and/or therapeutic biomarkers for SCZ.
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Authors
Hamid Mostafavi Abdolmaleky, Shabnam Nohesara, Mohammad Ghadirivasfi, Arthur W. Lambert, Hamidreza Ahmadkhaniha, Sait Ozturk, Chen Khuan Wong, Rahim Shafa, Ashraf Mostafavi, Sam Thiagalingam,