Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6825632 | Schizophrenia Research | 2014 | 10 Pages |
Abstract
The COGS-2 multi-site study detects schizophrenia-related PPI deficits reported in single-site studies, including patterns related to diagnosis, prepulse interval, sex, medication and other neurocognitive measures. Site differences were detected and explored. The target COGS-2 schizophrenia “endophenotype” of reduced PPI should prove valuable for identifying and confirming schizophrenia risk genes in future analyses.
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Authors
Neal R. Swerdlow, Gregory A. Light, Joyce Sprock, Monica E. Calkins, Michael F. Green, Tiffany A. Greenwood, Raquel E. Gur, Ruben C. Gur, Laura C. Lazzeroni, Keith H. Nuechterlein, Allen D. Radant, Amrita Ray, Larry J. Seidman, Larry J. Siever,