| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6826282 | Schizophrenia Research | 2013 | 9 Pages |
Abstract
This PKPD modelling approach can be helpful to differentiate the effect of antipsychotics across the different symptom domains of schizophrenia. Our analysis revealed that olanzapine seems to be superior in treating the negative symptoms compared to other non-clozapine SGAs. The relationship between receptor pharmacology profiles of the antipsychotics and their clinical efficacy is not yet fully understood.
Keywords
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Venkatesh Pilla Reddy, Magdalena Kozielska, Ahmed Abbas Suleiman, Martin Johnson, An Vermeulen, Jing Liu, Rik de Greef, Geny M.M. Groothuis, Meindert Danhof, Johannes H. Proost,