Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6827422 | Schizophrenia Research | 2012 | 7 Pages |
Abstract
Results suggest the effects of the BDNF Val66Met allele may be different in patients with psychosis than in healthy adults. Hippocampal volume in patient and control Met allele carriers was very similar suggesting that illness-related factors have minimal influence in this group. In contrast, Val homozygosity was related to smaller hippocampi and poorer memory functioning only in patients with psychosis.
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Authors
Geoffrey N. Smith, Allen E. Thornton, Donna J. Lang, G. William MacEwan, Thomas S. Ehmann, Lili C. Kopala, Karen Tee, Gillian Shiau, Aristotle N. Voineskos, James L. Kennedy, William G. Honer,