Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6827590 | Schizophrenia Research | 2011 | 7 Pages |
Abstract
FEP schizophrenia-spectrum and FEP affective-spectrum were similarly impaired in two biomarkers for schizophrenia. FEP subgroups showed impairments in fronto-central MMN consistent with chronic patients. Similarly, both subgroups showed reductions in P3a; although the affective subgroup showed an 'intermediate' frontal response. These findings suggest that FEP patients with both affective and schizophrenia spectrum diagnoses share common neurobiological disturbances in deviance detection/orienting processes in the early phase of illness.
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Manreena Kaur, Robert A. Battisti, Philip B. Ward, Arnab Ahmed, Ian B. Hickie, Daniel F. Hermens,