Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6828873 | Schizophrenia Research | 2008 | 8 Pages |
Abstract
Evidence supports harm avoidance as a schizophrenia-related endophenotype. An increased risk of schizophrenia may be associated with asociality (configured as high harm avoidance and low reward dependence), schizotypy (configured as low self-directedness, low cooperativeness, and high self-transcendence), and neurocognitive deficits (poor executive functioning, working/episodic memory, attention, and low IQ). The non-psychotic siblings demonstrated features of a mature character profile including strong crystallized IQ, which may confer protection against psychopathology.
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Authors
Matthew J. Smith, C. Robert Cloninger, Michael P. Harms, John G. Csernansky,