Article ID Journal Published Year Pages File Type
6829602 Schizophrenia Research 2007 5 Pages PDF
Abstract
Analysis of the distribution of mitochondrial haplogroups in schizophrenia patients compared to their healthy fathers (202 pairs) resulted in an over-representation of the mtDNA lineage cluster, HV, in the patients (p = 0.01), with increased relative risk (odds ratio) of 1.8. Since mitochondrial DNA is small relative to nuclear DNA, a total mitochondrial genome analysis was possible in a hypothesis-free manner. However, mitochondrial DNA haplogroups are highly variable in human population and it will be necessary to replicate our results in other human ethnic groups.
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Authors
, , , , , , , , , , , , ,