Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6897713 | European Journal of Operational Research | 2014 | 12 Pages |
Abstract
We present a Markov decision process (MDP) model to determine the optimal timing of blood pressure and cholesterol medications. We study the use of our model for a high-risk population of patients with type 2 diabetes; however, the model and methods we present are applicable to the general population. We compare the optimal policies based on our MDP to published guidelines for initiation of blood pressure and cholesterol medications over the course of a patient's lifetime. We also present a bicriteria analysis that illustrates the trade off between quality-adjusted life years and costs of treatment.
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Physical Sciences and Engineering
Computer Science
Computer Science (General)
Authors
J.E. Mason, B.T. Denton, N.D. Shah, S.A. Smith,